First bug report...sorry!
The bug: This happened on both the live discs for 32bit and 64bit. When I first moved the mouse, there was no action. I looked at the mouse, and the light wasn't on. I clicked the mouse button, and it started working. After letting it sit idle for about 5-10 seconds, it would go dead again. I'd have to click the mouse to get it working again. This happened during the entire time that I tried out both distros. As long as the mouse was active, it would work fine...but let it sit idle a few moments, and it goes dead.
Luckily, I had an old PS2 mouse that I could use on my old computer, and it worked fine without a problem.
My laptop though...at least the touchpad worked.
I went ahead and installed the 64bit onto a USB hoping an update might fix it...no luck there. So I just tried to see if I could figure out the problem...no luck there either. I found several web links describing similar problems, but nothing I tried worked...so...I'm at a loss.
I can't remember the brand of mouse I had on the old computer, but I use a Logitech on this laptop. I did see a package in Synaptic for Logitech, but its description didn't sound as though it would be of benefit, so I haven't installed it.